Depotime

Depotime is a brand name for dapoxetine, a medication primarily used to treat premature ejaculation (PE) in men aged 18 to 64. Unlike traditional selective serotonin reuptake inhibitors (SSRIs) prescribed off-label for PE, dapoxetine is specifically developed for this purpose and is taken on-demand, 1 to 3 hours before anticipated sexual activity.

Mechanism of Action

Dapoxetine functions by inhibiting the serotonin transporter, thereby increasing serotonin levels in the synaptic cleft. This action enhances ejaculatory control and prolongs the time to ejaculation. Its rapid absorption and elimination profile make it suitable for on-demand use, distinguishing it from other SSRIs that require daily dosing.

Efficacy and Safety

Clinical studies have demonstrated that dapoxetine significantly improves intravaginal ejaculatory latency time (IELT) and sexual satisfaction in men with PE. Common side effects include dizziness, nausea, and headache. These effects are generally mild and transient. Dapoxetine is contraindicated in individuals with certain cardiovascular conditions, bipolar disorder, and those taking monoamine oxidase inhibitors.

Availability

Depotime is available in various dosages, including 30 mg and 60 mg tablets. It is marketed under different brand names in various countries. In the United States, dapoxetine is not FDA-approved for PE treatment but is available in some countries under the brand name Priligy.

Conclusion

Depotime (dapoxetine) offers an effective and rapid-acting option for men seeking treatment for premature ejaculation. Its on-demand dosing regimen and targeted action provide a significant advancement in sexual medicine. As with any medication, it is essential to consult a healthcare provider to determine its suitability based on individual health profiles.